The effects of experimental knee pain on lower limb corticospinal and motor cortex excitability
Rice, DA; Graven-Nielsen, T; Lewis, GN; McNair, PJ; Dalbeth, N
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Notable weakness of the quadriceps muscles is typically observed as a consequence of knee joint arthritis, knee surgery and knee injury. This is partly due to ongoing neural inhibition that prevents the central nervous system from fully activating the quadriceps, a process known as arthrogenic muscle inhibition (AMI). To investigate the mechanisms underlying AMI, this study explored the effects of experimental knee pain on lower limb corticospinal and motor cortex excitability.