dc.contributor.author Henry, SM
dc.contributor.author Perry, HE
dc.date.accessioned 2011-11-28T00:31:43Z
dc.date.accessioned 2011-11-28T00:50:07Z
dc.date.available 2011-11-28T00:31:43Z
dc.date.available 2011-11-28T00:50:07Z
dc.date.copyright 2011-11-28
dc.date.issued 2011-11-28
dc.identifier.uri http://hdl.handle.net/10292/2827
dc.description.abstract Many teaching/training laboratories do not have access to a source of specimens that will give a full range of serologic reaction grades, or those representative of ABO weak subgroups. As a consequence many laboratory staff may lack a learning opportunity or continued experience in detecting weak serologic reactions. The ability to manually score serologic reactions is important particularly as part of disaster response planning, as laboratories may need to be relocated to areas without support of automated machines. In such situations staff need to be both competent and confident in their ability to manually perform serology. Group O RBCs can be controllably modified (koded) with blood group A and/or B Function-Spacer-Lipid (FSL) constructs to mimic the full serological range of weak ABO subgroups. These so-called kodecytes (KODE™ construct modified cells) already have a range of uses including quality control systems and will react with most monoclonal anti-A and B blood grouping reagents. The quality (sensitivity and specificity) of various monoclonal reagents varies significantly. This FSL-A+B(tri) Serologic Teaching Kit has been specifically designed for teaching purposes to create red cells (kodecytes) expressing reproducible and controlled levels of blood group A and B antigens to group O red cells. The aim is create kodecytes that can determine and improve the skill level of the operator to detect weak serologic agglutination reactions that may be encountered when blood typing weak phenotypes of blood group A or B. FSL-A+B(tri) Serologic Teaching Kit is a mixture of KODE™ technology FSL blood group A and B trisaccharide constructs designed for teaching/training purposes. This product contains a mixture of 0.5 mg of FSL-A(tri) and 1.5 mg of FSL-B(tri). All FSL constructs disperse in saline solutions and spontaneously and stably incorporate into cell membranes.
dc.publisher AUT University
dc.relation.ispartofseries number 20111128, pp.1 - 22
dc.relation.replaces http://hdl.handle.net/10292/2826
dc.relation.replaces 10292/2826
dc.relation.isreplacedby 10292/2828
dc.relation.isreplacedby http://hdl.handle.net/10292/2828
dc.rights The information in this document is provided copyright free and public domain. It may be modified, reproduced, used, derivatized and distributed in any form
dc.title FSL-A+B(tri) Serologic teaching kit
dc.type Commissioned Report
dc.rights.accessrights OpenAccess

Search Scholarly Commons

Advanced Search


Theses and Dissertations

About Scholarly Commons

Usage Statistics


  • Bookmark and Share