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Search Results for Collection: School of Applied Sciences

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Development and validation of antibody screening cells specifically designed for Asian populations - the first example of the addition of peptide antigens to human red cells using KODE technology

Heathcote, D; Henry, S; Flower, R (AUT University, Blackwell Publishing Ltd; 2008)

Background: Alloantibodies to antigens displayed on variant glycophorins are common in many Asian populations and have been shown to cause both transfusion reactions and haemolytic disease of the foetus and newborn new ...
Flow cytometric evaluation of red blood cells transformed with variable amounts of synthetic A and B glycolipids

Hult, K; Frame, T; Henry, S; Olsson, ML (AUT University, Blackwell Publishing Ltd; 2008)

Background: According to national guidelines or directives, monoclonal ABO reagents may be required to detect Ax and B weak subgroup red blood cells (RBCs). Many routine laboratories do not have access to naturallyoccurring ABO ...
Fluorophore-kodecytes - fluorescent function-spacer-lipid (FSL) modified cells for in vitro and in vivo analyses

Blake, D; Lan, A; Love, D; Bovin, N; Henry, S (AUT University, John Wiley & Sons Ltd; 2010)

Most live cells are naturally poorly visible and so various secondary techniques, such as staining (including fluorescent tagging), are used to visualize them. However, a major limitation of most staining techniques is ...
Function-Spacer-Lipid (FSL) constructs enable inkjet printing of blood group antigens

Barr, K; Diegel, O; Parker, S; Bovin, N; Henry, S (AUT University, John Wiley & Sons Ltd; 2010)

A limitation of inkjet printing antigens to solid surfaces is that the molecule to be printed must be dispersible in solution, retain antigenicity, and remain on the printed surface when exposed to biological solutions. ...
Syphilis-kodecytes - novel function-spacer-lipid (FSL) modified red cells capable of sensitive and specific detection of syphilis antibodies

Komarraju, S; Chesla, S; Bovin, N; Henry, S (AUT University, John Wiley & Sons Ltd; 2010)

The ability to detect infectious agents is a prerequisite to the treatment and containment of transmittable diseases. Many diagnostics assays are based upon the detection of antibodies in serum against the infectious agent ...
Biotin-kodecytes - novel function-spacer-lipid (FSL) modified cells capable of being recovered from the circulation after 3 days

Oliver, C; Blake, D; Ferguson, S; Bovin, N; Henry, S (AUT University, John Wiley & Sons Ltd; 2010)

The ability to modify a population of blood cells with both an antigen of interest and an identification-recovery label, infuse them into the circulation of an animal, and then visualize or recover a sample of the infused ...
The development of synthetic peptidolipids, glycolipids and other lipid-linked structures to create designer red cells

Henry, S; Bovin, N (John Wiley & Sons, AUT University; 2008)

Background: Red cells used in immunohematology assays are restricted by their natural phenotype and membrane characteristics. More recently a technology has been developed which allows for the attachment of a large variety ...
Videos relating to Fluorescent Function-Spacer-Lipid construct labeling allows for real-time in vivo imaging of cell migration and behaviour in zebrafish (Danio rerio)

Lan, C-C; Blake, D; Henry, S; Love, D (AUT University; 2012)

Video descriptions: Video 1: 2 hours post injection imaging of the caudal vein plexus area of 52 hpf recipient zebrafish receiving 0.2 mg/ml FSL-FLRO4-I transformed WKM cells. In the video, a large slow-moving cell ...