NISAN - the National Institute for Stroke and Applied Neurosciences
Institute Director: Professor Valery Feigin
Deputy Director: Associate Professor Alice Theadom
The National Institute for Stroke and Applied Neurosciences (NISAN) conducts epidemiological studies and clinical trials to improve health and outcomes in people with major neurological disorders. Current research programmes focus on:
- Traumatic brain injury
- Neuromuscular disorders
- Public health
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The Global Burden of Mental, Neurological and Substance Use Disorders: An Analysis From the Global Burden of Disease Study 2010 (PLOS, 2015)Background The Global Burden of Disease Study 2010 (GBD 2010), estimated that a substantial proportion of the world’s disease burden came from mental, neurological and substance use disorders. In this paper, we used GBD ...
Global, Regional, and National Life Expectancy, All-cause Mortality, and Cause-specific Mortality for 249 Causes of Death, 1980-2015: A Systematic Analysis for the Global Burden of Disease Study 2015 (Elsevier, 2016)Background Improving survival and extending the longevity of life for all populations requires timely, robust evidence on local mortality levels and trends. The Global Burden of Disease 2015 Study (GBD 2015) provides a ...
Global, Regional, and National Incidence, Prevalence, and Years Lived With Disability for 310 Acute and Chronic Diseases and Injuries, 1990-2015: A Systematic Analysis for the Global Burden of Disease Study 2015 (Elsevier, 2016)Background Non-fatal outcomes of disease and injury increasingly detract from the ability of the world's population to live in full health, a trend largely attributable to an epidemiological transition in many countries ...
Global, Regional, and National Comparative Risk Assessment of 79 Behavioural, Environmental and Occupational, and Metabolic Risks or Clusters of Risks, 1990-2015: A Systematic Analysis for the Global Burden of Disease Study 2015 (Elsevier, 2016)Background The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 provides an up-to-date synthesis of the evidence for risk factor exposure and the attributable burden of disease. By providing national and ...
Global, Regional, and National Disability-adjusted Life Years (Dalys) for 315 Diseases and Injuries and Healthy Life Expectancy (Hale), 1990-2015: A Systematic Analysis for the Global Burden of Disease Study 2015 (Elsevier, 2016)Background Healthy life expectancy (HALE) and disability-adjusted life-years (DALYs) provide summary measures of health across geographies and time that can inform assessments of epidemiological patterns and health ...
(Mary Ann Liebert, Inc., 2015)This systematic review provides a comprehensive, up-to-date summary of traumatic brain injury (TBI) epidemiology in Europe, describing incidence, mortality, age, and sex distribution, plus severity, mechanism of injury, ...
(BioMed Central Ltd., 2015)Background: Previous qualitative research has revealed that people with fibromyalgia use daytime napping as a coping strategy for managing symptoms against clinical advice. Yet there is no evidence to suggest whether daytime ...
Collaborative European Neurotrauma Effectiveness Research in Traumatic Brain Injury (Center-tbi): A Prospective Longitudinal Observational Study (Congress of Neurological Surgeons, 2015)BACKGROUND: Current classification of traumatic brain injury (TBI) is suboptimal, and management is based on weak evidence, with little attempt to personalize treatment. A need exists for new precision medicine and stratified ...
The Effect of Spinal Position on Sciatic Nerve Excursion During Seated Neural Mobilisation Exercises: An in Vivo Study Using Ultrasound Imaging (Taylor & Francis, 2016)Objectives: Research has established that the amount of inherent tension a peripheral nerve tract is exposed to influences nerve excursion and joint range of movement (ROM). The effect that spinal posture has on sciatic ...
Development of the Standards of Reporting of Neurological Disorders (Strond) Checklist: A Guideline for the Reporting of Incidence and Prevalence Studies in Neuroepidemiology (Wolters Kluwer, 2016)Background: Incidence and prevalence studies of neurologic disorders play an important role in assessing the burden of disease and planning services. However, the assessment of disease estimates is hindered by problems in ...
Measuring the Health-related Sustainable Development Goals in 188 Countries: A Baseline Analysis From the Global Burden of Disease Study 2015 (Elsevier, 2016)Background In September, 2015, the UN General Assembly established the Sustainable Development Goals (SDGs). The SDGs specify 17 universal goals, 169 targets, and 230 indicators leading up to 2030. We provide an analysis ...
Reliable Individual Change in Post Concussive Symptoms in the Year Following Mild Traumatic Brain Injury: Data From the Longitudinal, Population-based Brain Injury Incidence and Outcomes New Zealand in the Community (Bionic) Study (JSciMed Central, 2016)Objective: Post concussive syndromes (PCS) is common after mild-TBI, yet are not well studied on a population level. This study examined PCS symptoms, including reliable change over time in a population-based sample up ...